Articles
18 October 2024
Vol. 46 No. 2 (2024)
https://doi.org/10.4081/pmc.2024.337

Morbidity related to major lung thoracoscopic resections in children

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Lung, respiratory system abnormalities, video-assisted thoracic surgery, thoracoscopy, postoperative complications, clavien-dindo
1924
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Authors

Sara Ugolini
Sara.ugolini13@studio.unibo.it
https://orcid.org/0000-0001-7150-6082
Thoracic Surgery Department, Barts Thorax Centre, St Bartholomew’s Hospital, Barts NHS Fuondation Trust, London, United Kingdom; Ph.D. in Cardio-Nephro-Thoracic Sciences, Department of Medical and Surgical Sciences, Alma Mater Studiorum Università di Bologna, Italy.
Lorenzo Tofani
https://orcid.org/0000-0001-9965-7667
Department of Statistics, Informatics, Applications, University of Florence, Italy.
Elisa Zolpi
Department of Pediatric Surgery, Pediatric Minimally Invasive Surgery and New Technologies, San Bortolo Hospital, Vicenza, Italy.
Louise Montalva
Department of Pediatric Surgery and Urology, Robert-Debré University Hospital, Paris, France.
Cosimo Lotti
Physiotherapy Department, Princess Royal University Hospital, King’s College Hospital NHS Foundation Trust, London, United Kingdom.
Antonino Morabito
Department of Pediatric Surgery, IRCCS – Azienda Ospedaliero Universitaria Meyer, University of Florence, Italy.
Fabio Chiarenza
https://orcid.org/0000-0001-7822-2963
Department of Pediatric Surgery, Pediatric Minimally Invasive Surgery and New Technologies, San Bortolo Hospital, Vicenza, Italy.
Arnaud Bonnard
Department of Pediatric Surgery and Urology, Robert-Debré University Hospital, Paris, France; Paris University, Paris, France; Université Paris Diderot-Sorbonne Paris Cité, Paris, France.

In pediatric thoracic surgery, reported predictors for increased risk are symptoms and active/previous infections (RAP). We investigated the adverse events related to Video-Assisted Thoracic Surgery (VATS) in pediatric patients when considering RAP predictors. A retrospective analysis of pediatric VATS major lung resections in 2008-2021 was conducted at three institutions. We employed the pediatric surgical risk calculator to define patients’ preoperative predicted risk (PredR). Postoperative complications were classified according to the Thoracic Morbidity & Mortality (TM&M) system. The observed TM&M rate (ObsR) and the PredR were compared. A subgroup analysis by RAP predictors was conducted. 37 patients (54% female) were included. Mean age and weight were 5.8 years and 22.8 kg. 56.7% had respiratory symptoms, 38.9% active infection and 59.5% history of infections (RAP subpopulations). VATS procedures were lobectomy (n=32), segmentectomy (n=3), bilobectomy (n=1) and pneumonectomy (n=1). The conversion rate was 5.4%. The mean PredR was of 4.43% (±1.8) and the overall ObsR was 45.94% with a median severity of II (I-III). This difference was significant and a higher PredR was not associated with complications development. PredR does not show association among the RAP vs non-RAP group. ObsR showed positive association with RAP, even if it reached statistical significance only for “respiratory symptoms” risk factor. ObsR reflected the number of bronchiectasis patients in our series (n=9), aligning with the hypothesis of “earlier and safer surgery”. The risk calculator underestimates VATS morbidity. Multicentre studies will clarify the correlation between inflammation and surgical adverse events.

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Morbidity related to major lung thoracoscopic resections in children. (2024). La Pediatria Medica E Chirurgica, 46(2). https://doi.org/10.4081/pmc.2024.337
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