Ibuprofen versus steroids: risk and benefit, efficacy and safety


Submitted: 17 November 2014
Accepted: 17 November 2014
Published: 31 October 2013
Abstract views:
1892


PDF:
26210
Publisher's note
All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers. Any product that may be evaluated in this article or claim that may be made by its manufacturer is not guaranteed or endorsed by the publisher.

Authors

  • M. Giovannini Professore Emerito di Pediatria, Università degli Studi di Milano, Milano, Italy.
  • M. Mandelli Clinica Pediatrica, Ospedale S. Paolo, Università degli Studi di Milano, Milano, Italy.
  • C. Gualdi Clinica Pediatrica, Ospedale S. Paolo, Università degli Studi di Milano, Milano, Italy.
  • S. Palazzo Clinica Pediatrica, Ospedale S. Paolo, Università degli Studi di Milano, Milano, Italy.
In the last few years we have observed an upward trend in the employment of ibuprofen as anti-inflammatory and antipyretic therapy. Therefore the pediatrician has often a precious option in the anti-inflammatory and antipyretic treatment in children instead of using steroids and paracetamol. In clinical practice ibuprofen can be used in the treatment of headache, toothache, otalgy, dysmenorrhea, neuralgia, arthralgia, myalgia, abdominal pain and fever: it is the first choice for these common diseases. However, the use of steroids is a routine, even if non-corticosteroid anti-inflammatory molecules could be useful. Certainly steroids are powerful anti-inflammatory, indicated for the treatment of chronic inflammatory disorders and in acute respiratory and allergic diseases. Beside, thanks to their chemical and pharmacological profile, they also provide patients with an antipyretic effect. However, the use of steroids must be reserved to cases in which other classical antipyretics such as non-steroidal anti-inflammatory drugs are not effective. The possible side effects and risks associated with stepping down steroids must be considered. Although “steroids-phobia†should be discouraged, steroids are to be reserved only as the first indication. In all other cases the pediatrician can use ibuprofen, whose efficacy and safety are widely demonstrated by now.

Giovannini, M., Mandelli, M., Gualdi, C., & Palazzo, S. (2013). Ibuprofen versus steroids: risk and benefit, efficacy and safety. La Pediatria Medica E Chirurgica, 35(5). https://doi.org/10.4081/pmc.2013.28

Downloads

Download data is not yet available.

Citations