La Pediatria Medica e Chirurgica http://www.pediatrmedchir.org/index.php/pmc <p><strong>La Pediatria Medica e Chirurgica&nbsp;</strong>(Medical and Surgical Pediatrics) publishes original papers in the field of basic science, clinical and laboratory research pertinent to medical and surgical pediatrics.</p> <p>In addition to Original Articles, <strong>La Pediatria Medica e Chirurgica&nbsp;</strong>(Medical and Surgical Pediatrics) welcomes Editorials (on invitation), Brief Reports, Letters to the Editor and Book Reviews as well. All manuscripts are critically assessed by external and/or in-house experts in accordance with the principles of peer review. Manuscripts must be written in English or Italian.</p> en-US <p><strong>PAGEPress</strong> has chosen to apply the&nbsp;<a href="http://creativecommons.org/licenses/by-nc/4.0/" target="_blank" rel="noopener"><strong>Creative Commons Attribution NonCommercial 4.0 International License</strong></a>&nbsp;(CC BY-NC 4.0) to all manuscripts to be published.<br><br> An Open Access Publication is one that meets the following two conditions:</p> <ol> <li>the author(s) and copyright holder(s) grant(s) to all users a free, irrevocable, worldwide, perpetual right of access to, and a license to copy, use, distribute, transmit and display the work publicly and to make and distribute derivative works, in any digital medium for any responsible purpose, subject to proper attribution of authorship, as well as the right to make small numbers of printed copies for their personal use.</li> <li>a complete version of the work and all supplemental materials, including a copy of the permission as stated above, in a suitable standard electronic format is deposited immediately upon initial publication in at least one online repository that is supported by an academic institution, scholarly society, government agency, or other well-established organization that seeks to enable open access, unrestricted distribution, interoperability, and long-term archiving.</li> </ol> <p>Authors who publish with this journal agree to the following terms:</p> <ol> <li>Authors retain copyright and grant the journal right of first publication with the work simultaneously licensed under a Creative Commons Attribution License that allows others to share the work with an acknowledgement of the work's authorship and initial publication in this journal.</li> <li>Authors are able to enter into separate, additional contractual arrangements for the non-exclusive distribution of the journal's published version of the work (e.g., post it to an institutional repository or publish it in a book), with an acknowledgement of its initial publication in this journal.</li> <li>Authors are permitted and encouraged to post their work online (e.g., in institutional repositories or on their website) prior to and during the submission process, as it can lead to productive exchanges, as well as earlier and greater citation of published work.</li> </ol> francesca.baccino@pagepress.org (Francesca Baccino) tiziano.taccini@pagepress.org (Tiziano Taccini) Fri, 18 Jan 2019 16:18:40 +0100 OJS 3.1.1.0 http://blogs.law.harvard.edu/tech/rss 60 Paediatric surgery in the robotic era: early experience and comparative analysis http://www.pediatrmedchir.org/index.php/pmc/article/view/204 <p>The aim of this study is to present our preliminary experience in robotics and a comparative analysis with conventional Minimally- Invasive Surgery (MIS). Cases operated by da Vinci Xi® System from February 2016 to October 2017 are reviewed retrospectively through demographics, diagnosis-procedure and short-term outcome parameters. A comparison with a matching conventional MIS population was also conducted. 40 robotic procedures were carried out and 112 (out of 3705) non-robotic procedures met inclusion criteria for comparison. Among robotic patients we observed: an average age of 143.5 months, weight of 42.9 Kg, operative and anaesthesia induction time respectively of 116.8 and 34.8 minutes. Furthermore, we observed a 6.1-day length of stay, 2.5% conversion rate and no complications. From the comparison between the groups, no statistical difference emerged in the length of stay, in conversion rates or in complications. A statistical significance was observed in terms of operative time in favour of non-Robotic- System. Our experience has meant to introduce the System in our surgical environment, comparing to the conventional MIS (an already established approach routinely performed at our center). Results have shown comparable safety and feasibility.</p> Mario Lima, Eduje Thomas, Neil Di Salvo, Tommaso Gargano, Giovanni Ruggeri ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/204 Fri, 18 Jan 2019 16:16:14 +0100 Hypoceruloplasminemia: an unusual biochemical finding in a girl with Hashimoto's thyroiditis and severe hypothyroidism http://www.pediatrmedchir.org/index.php/pmc/article/view/179 <p>Clinical picture of Hashimoto’s thyroiditis (HT) may significantly vary in pediatric age, ranging from euthyroidism to subclinical hypothyroidism or hyperthyroidism; only rarely HT presentation may be characterized by a severe hypothyroidism also in pediatric age. Here we describe a 3-year-old Caucasian girl who was admitted to our Clinic due to pericardial effusion, muscle weakness and weight gain. At clinical examination, she presented with bradycardia, pale and round face, pseudohypertrophy of calf muscles and no pitting edema of the limbs. Routine blood investigations showed high serum aspartate and alanine aminotransferase levels, low serum ceruloplasmin without clinical signs of Wilson’s disease, dyslipidemia. Thyroid function tests revealed a picture of severe hypothyroidism associated with HT. After the replacement treatment with L-T4, thyroid-stimulating hormone serum levels gradually decreased, with concomitant resolution of pericardial effusion and normalization of ceruloplasmin levels.</p> Mariella Valenzise, Federica Porcaro, Giuseppina Zirilli, Filippo De Luca, Maurizio Cinquegrani, Tommaso Aversa ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/179 Wed, 05 Dec 2018 09:50:08 +0100 Robot-assisted resection of gastric duplication cysts in a child: a detailed case report http://www.pediatrmedchir.org/index.php/pmc/article/view/203 <p>Gastric duplication cysts (GDCs) represent 4-9% of alimentary tract duplications. Early diagnosis and surgical excision are essential to avoid morbidity or neoplastic degeneration. Roboticassisted excision of GDCs has never been described in childhood. We report an asymptomatic male patient with 2 gastric cystic masses at ultrasonography (US)-study (diameter 25mm and 8mm), increasing in size at follow-up. At 20 months of age, magnetic- resonance-imaging-scan confirmed 2 round gastric masses (44×35mm and 16×12mm, respectively). Two months later, an elective robotic-assisted excision of GDCs was completed without complications. The patient was discharged at day 6 after procedure. Histology confirmed the diagnosis of GDCs. At a 2-year follow- up, US-study did not evidence any issue. In this first reported case of robotic-assisted cystectomy for CGD in childhood, the procedure seems safe, effective, and feasible. This approach improves the movements of the surgical instruments with better 3- D visualization in comparison with the laparoscopic approach.</p> Riccardo Rizzo, Gabriele Lisi, Nino Marino, Giuseppe Lauriti, Dacia Di Renzo, Pierluigi Lelli Chiesa ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/203 Tue, 04 Dec 2018 11:16:12 +0100 The isolated tubal torsion: an insidious pediatric and adolescent pelvic urgency http://www.pediatrmedchir.org/index.php/pmc/article/view/206 <p>Isolated tubal torsion (ITT) is a rare cause of acute abdominal pain. Preoperative diagnosis is difficult because of a lack of specific signs. Surgery is recommended to preserve the integrity of the tube. Seven patients of median age of 13 years (range 9 to 15) came to our observation for worsening abdominal pain, nausea and vomiting. On admission, all girls had blood tests and ultrasound. Laparoscopy was performed for diagnosis in all cases. The girls had one-month and one-year ultrasound and clinic follow up. In all cases diagnosis was delayed, median 66 hours after the onset of symptoms and laparoscopy showed necrosis of the Fallopian tube. In five girls a laparoscopic salpingectomy was performed. In the other two, an open salpingectomy was necessary because of pelvic adhesions. Histology showed a hemorrhagic infarction of the Fallopian tubes. At follow up all patients were asymptomatic with normal ovaries, but one ovarian cyst. In the differential diagnosis of acute abdominal pain in children or female adolescents the possibility of ITT should be considered for a conservative treatment. Laparoscopy allows for definitive diagnosis and treatment.</p> Carmine Noviello, Mercedes Romano, Alfonso Papparella, Andrea Ciavattini, Ascanio Martino, Giovanni Cobellis ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/206 Tue, 04 Dec 2018 11:05:58 +0100 Pseudoarthrosis of second metatarsal fracture http://www.pediatrmedchir.org/index.php/pmc/article/view/205 <p>Metatarsal fractures make up the greatest portion of foot fractures in children. Most of them are treated with closed reduction and non-weightbearing cast immobilization.Usually, these fractures heal uneventfully and delay union and pseudoarthrosis are rare. We report a case of a 10-year-old child with non-union of the second metatarsal following a traumatic fracture, caused by an accident 10 months before, and treated successfully by osteosynthesis with plate and screws. Good clinical outcome was achieved at 2 years follow-up.</p> Jessica Zanovello, Barbara Bertani, Redento Mora, Gabriella Tuvo, Mario Mosconi, Luisella Pedrotti ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/205 Fri, 19 Oct 2018 15:24:56 +0200 Transscrotal orchidopexy for palpable cryptorchid testis: follow-up and outcomes http://www.pediatrmedchir.org/index.php/pmc/article/view/191 <p>We retrospectively reviewed the results of transscrotal orchidopexy in the surgical management of palpable testis. From January 2014 to June 2017, 130 male children with a total of 140 palpable undescended testes (UDT) underwent transscrotal orchidopexy. The charts were retrospectively reviewed for demographic data, preoperative position and mobility of the testis, patency of the peritoneal vaginal duct (PVD), and post-operative complications. The resting position of the testis and its traction towards the scrotum were assessed before surgery and under anaesthesia. The mean age of the patients was 4.6 years. The position of the testis assessed at surgery was in most cases at the external inguinal ring (62.8%), at the neck of the scrotum (15.7%), in the inguinal canal (12.8%), or in an ectopic position (8,5%). A PVD was found in 66 testes (47.1%). Two surgical cases required an inguinal incision. In each patient, the postoperative course was unremarkable. The testicle at 1-year follow-up was in a scrotal position in 134 cases, but 6 patients required a second surgical intervention for re-ascent of the testis. No testicular atrophy or inguinal hernias were observed. Transscrotal orchidopexy is a simple and effective procedure for the treatment of palpable UDT. The incidence of complications is low and manageable, with rapid postoperative recovery and early resumption of normal activities.</p> Alfonso Papparella, Giovanni Cobellis, Laura De Rosa, Carmine Noviello ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/191 Wed, 03 Oct 2018 11:59:45 +0200 Clinical side effects after oral administration of palm oil and Alchornea cordifolia decoction in a child http://www.pediatrmedchir.org/index.php/pmc/article/view/152 <p><em>Alchornea cordifolia</em> is known to be a plant with a variety of medicinal properties and is quoted by many traditional healers to treat a variety of medicinal problems in the Democratic Republic of Congo. However, very little is known about its potential toxicity. We report the case of a 9-year-old boy referred for assessment of suspected bronchial troubles without a history of atopic disease or drug allergy who developed dyspnea, dysphagia, asthenia and lingual ulcers within 30 minutes after nasal and oral administration of decoction of palm oil associated with <em>A. cordifolia</em> leaves in water. In the present report, adverse effects of <em>A. cordifolia</em> therapy may be related to the mixtures of active compounds that they contain and can cause the symptoms observed in our patient. These findings call for caution in the use of <em>A. cordifolia</em> especially in children.</p> Paulo Muntu Bunga, Jephté Bambi Nzita, Gerry Mubungu, Sophie Nyembo Mangaza, Nono Joelle Seudjip, Michel Ntetani Aloni ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/152 Wed, 26 Sep 2018 12:08:16 +0200 Transient femoral nerve palsy in spica cast treatment for developmental dysplasia of the hip http://www.pediatrmedchir.org/index.php/pmc/article/view/200 <p>A 4 months and half female child come to our attention for congenital dislocation of the left hip, previously treated in another hospital with abduction bracing, without satisfactory results. After progressive longitudinal bilateral traction, closed reduction under general anesthesia was performed and a spica cast was applied in the so-called<em> human position</em>. The patients remained in the spica cast for 6 weeks and then the plaster cast was renewed in narcosis for another 6 weeks. Once the second cast has been removed left femoral nerve palsy was detected. Orthopaedic treatment was interrupted and in 3 months the nerve completely recovered, while the hip was still stable. We followed the child regularly since then, she is now five years old, she is totally asymptomatic, X-rays shows a residual acetabular dysplasia, with no sign of avascular necrosis.</p> Luisella Pedrotti, Barbara Bertani, Gabriella Tuvo, Redento Mora, Mario Mosconi, Federica De Rosa ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/200 Wed, 26 Sep 2018 12:00:00 +0200 Robotic removal of Müllerian duct remnants in pediatric patients: our experience and a review of the literature http://www.pediatrmedchir.org/index.php/pmc/article/view/182 <p>Persistent Müllerian duct syndrome is a disorder of sexual development, which features a failure of involution of Müllerian structures. An enlarged prostatic utricle is a kind of Müllerian duct remnant (MDR) with a tubular shaped structure communicating with the prostatic urethra. Treatment is aimed at relieving symptoms when present, preserve fertility and prevent neoplastic degeneration. We describe 3 cases of successful robot assisted-removal of symptomatic MDRs. The first case came to our attention for pseudo-incontinence; the other two for recurrent urinary tract infections. The patients have not presented such symptoms anymore on follow-up. We then reviewed existent literature on authors who have recently investigated the main issues concerning MDRs and have attempted a roboticassisted approach on them. Robot-assisted laparoscopy can be considered a valid, safe and effective minimally-invasive technique for the primary treatment of prostatic utricle.</p> Mario Lima, Michela Maffi, Niel Di Salvo, Giovanni Ruggeri, Michele Libri, Tommaso Gargano, Hubert Lardy ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/182 Wed, 30 May 2018 17:33:38 +0200 Kearns-Sayre syndrome is genetically and phenotypically heterogeneous http://www.pediatrmedchir.org/index.php/pmc/article/view/193 <p>Not available.</p> Josef Finsterer, Sinda Zarrouk-Mahjoub ##submission.copyrightStatement## http://creativecommons.org/licenses/by-nc/4.0 http://www.pediatrmedchir.org/index.php/pmc/article/view/193 Tue, 29 May 2018 11:40:49 +0200